Solubility of n-(4-Ethoxyphenyl)ethanamide in Supercritical Carbon Dioxide
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  • 作者:Rajasekhar Ch ; Chandrasekhar Garlapati ; Giridhar Madras
  • 刊名:Journal of Chemical & Engineering Data
  • 出版年:2010
  • 出版时间:March 11, 2010
  • 年:2010
  • 卷:55
  • 期:3
  • 页码:1437-1440
  • 全文大小:134K
  • 年卷期:v.55,no.3(March 11, 2010)
  • ISSN:1520-5134
文摘
The solubility of a drug, n-(4-ethoxyphenyl)ethanamide (phenacetin), in supercritical carbon dioxide was determined by a saturation method at (308, 318, and 328) K from (9 to 19) MPa. The solubilities in mole fraction of n-(4-ethoxyphenyl)ethanamide in supercritical carbon dioxide were in the range of 1.29·10−5 to 2.88·10−5, 1.13·10−5 to 3.65·10−5, and 0.91·10−5 to 4.28·10−5 at (308, 318, and 328) K, respectively. The solubility data were correlated with the Peng−Robinson equation of state models and the Mndez-Santiago and Teja model.

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