文摘
The solubility of a drug, n-(4-ethoxyphenyl)ethanamide (phenacetin), in supercritical carbon dioxide was determined by a saturation method at (308, 318, and 328) K from (9 to 19) MPa. The solubilities in mole fraction of n-(4-ethoxyphenyl)ethanamide in supercritical carbon dioxide were in the range of 1.29·10−5 to 2.88·10−5, 1.13·10−5 to 3.65·10−5, and 0.91·10−5 to 4.28·10−5 at (308, 318, and 328) K, respectively. The solubility data were correlated with the Peng−Robinson equation of state models and the Mndez-Santiago and Teja model.