Novel Ionophores with 2n-Crown-n Topology: Anion Sensing via Pure Aliphatic C–H···Anion Hydrogen Bonding
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- 作者：Genggongwo Shi ; Changdev G. Gadhe ; Sung-Woo Park ; Kwang S. Kim ; Jongmin Kang ; Humaira Seema ; N. Jiten Singh ; Seung Joo Cho
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：January 17, 2014
- 年：2014
- 卷：16
- 期：2
- 页码：334-337
- 全文大小：238K
- ISSN：1523-7052
文摘
A series of novel coronands having a 2n-crown-n topology based on trioxane (6-crown-3) derivatives are designed and characterized. These neutral hosts can sense anions through pure aliphatic C鈥揌 hydrogen bonding (HB) in condensed phases due to the unusual topology of 2n-crown-n. C鈥揌 bonds are strongly polarized by two adjacent oxygen atoms in this scaffold. These hosts provide a rare opportunity to modulate anion binding strength by changing the electronic nature of aliphatic C鈥揌 bonds and offer ease of synthesis.