文摘
This study was designed to determine the body burden ofpolybrominated diphenyl ethers (PBDEs) among first-time mothers in the Greater Boston, Massachusetts areaand to explore key routes of exposure. We collected breastmilk samples from 46 first-time mothers, 2-8 weeksafter birth. We also sampled house dust from the homesof a subset of participants by vacuuming commonly usedareas. Data on personal characteristics, diet, homefurniture, and electrical devices were gathered from eachparticipant using a questionnaire. Breast milk and dustsamples were analyzed for PBDEs using gas chromatography/mass spectrometry. PBDE concentrations were log-normally distributed in breast milk and dust. We foundstatistically significant, positive associations between PBDEconcentrations in breast milk and house dust (r = 0.76,p = 0.003, not including BDE-209), as well as with reporteddietary habits, particularly the consumption of dairyproducts (r = 0.41, p = 0.005) and meat (r = 0.37, p =0.01). Due to low detection rates, it was not possible to drawconclusions about the association between BDE-209 inmilk and dust. Our results support the hypothesis that theindoor environment and diet both play prominent rolesin adult human exposure to PBDEs.