Intramolecular sp3 Functionalization of Cyclopropyl α-Amino Acid-Derived Benzamides

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• 作者：Carolyn L. Ladd ; Audrey V. Belouin ; André B. Charette
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：January 4, 2016
• 年：2016
• 卷：81
• 期：1
• 页码：256-264
• 全文大小：428K
• ISSN：1520-6904

文摘

Intramolecular Pd-catalyzed functionalization of cyclopropyl α-amino acid-derived benzamides proceeds without silver or pivalate additives. Both electronically and sterically diverse ethyl 1,2,3,4-tetrahydroisoquinolone-3-carboxylates were accessible in good to excellent yields.