PPh3-Substituted [2,5-Ph2-3,4-Tol2(5-C4COH)]Ru(CO)(PPh3)H Exhibits S
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- 作者：Charles P. Casey ; Neil A. Strotman ; Sharon E. Beetner ; Jeffrey B. Johnson ; David C. Priebe ; and Ilia A. Guzei
- 刊名：Organometallics
- 出版年：2006
- 出版时间：February 27, 2006
- 年：2006
- 卷：25
- 期：5
- 页码：1236 - 1244
- 全文大小：172K
- 年卷期：v.25,no.5(February 27, 2006)
- ISSN：1520-6041
文摘
The PPh3-substituted hydroxycyclopentadienyl ruthenium hydride [2,5-Ph2-3,4-Tol2(
5-C4COH)]Ru(CO)(PPh3)H (1) stoichiometrically reduces aldehydes and ketones in the presence of a pyridine trapto produce alcohols and the ruthenium pyridine complex 5, with a rate law that is dependent only on[aldehyde] and [1]. The observation of deuterium kinetic isotope effects on substitution of the acidic andhydridic protons of 1 are consistent with concerted transfer of hydrogen to aldehydes during reduction.1 catalytically hydrogenates aldehydes under mild temperature and pressure conditions. While the Shvocatalyst 2 shows little activity under these conditions, it surpasses 1 at elevated temperatures and pressures.1 shows high chemoselectivity for catalytic hydrogenation of aldehydes over ketones, while 2 is muchless selective.
5-C4COH)]Ru(CO)(PPh3)H (1) stoichiometrically reduces aldehydes and ketones in the presence of a pyridine trapto produce alcohols and the ruthenium pyridine complex 5, with a rate law that is dependent only on[aldehyde] and [1]. The observation of deuterium kinetic isotope effects on substitution of the acidic andhydridic protons of 1 are consistent with concerted transfer of hydrogen to aldehydes during reduction.1 catalytically hydrogenates aldehydes under mild temperature and pressure conditions. While the Shvocatalyst 2 shows little activity under these conditions, it surpasses 1 at elevated temperatures and pressures.1 shows high chemoselectivity for catalytic hydrogenation of aldehydes over ketones, while 2 is muchless selective.