Salicylimine-Based Fluorescent Chemosensor for Aluminum Ions and Application to Bioimaging

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• 作者：Soojin Kim ; Jin Young Noh ; Ka Young Kim ; Jin Hoon Kim ; Hee Kyung Kang ; Seong-Won Nam ; So Hyun Kim ; Sungsu Park ; Cheal Kim ; Jinheung Kim
• 刊名：Inorganic Chemistry
• 出版年：2012
• 出版时间：March 19, 2012
• 年：2012
• 卷：51
• 期：6
• 页码：3597-3602
• 全文大小：388K
• 年卷期：v.51,no.6(March 19, 2012)
• ISSN：1520-510X

文摘

In this study, an assay to quantify the presence of aluminum ions using a salicylimine-based receptor was developed utilizing turn-on fluorescence enhancement. Upon treatment with aluminum ions, the fluorescence of the sensor was enhanced at 510 nm due to formation of a 1:1 complex between the chemosensor and the aluminum ions at room temperature. As the concentration of Al³⁺ was increased, the fluorescence gradually increased. Other metal ions, such as Na⁺, Ag⁺, K⁺, Ca²⁺, Mg²⁺, Hg²⁺, Mn²⁺, Co²⁺, Ni²⁺, Cu²⁺, Zn²⁺, Cd²⁺, Pb²⁺, Cr³⁺, Fe³⁺, and In³⁺, had no such significant effect on the fluorescence. In addition, we show that the probe could be used to map intracellular Al³⁺ distribution in live cells by confocal microscopy.