Palladium-Catalyzed Migratory Insertion of Isocyanides for Synthesis of C-Phosphonoketenimines

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• 作者：Qiang Yang ; Chong Li ; Ming-Xing Cheng ; Shang-Dong Yang
• 刊名：ACS Catalysis
• 出版年：2016
• 出版时间：July 1, 2016
• 年：2016
• 卷：6
• 期：7
• 页码：4715-4719
• 全文大小：466K
• 年卷期：0
• ISSN：2155-5435

文摘

An efficient method for the synthesis of C-phosphonoketenimines through palladium-catalyzed migratory insertion of isocyanides has been developed for the first time. This procedure tolerates wide functional groups and has a good atom economy. Further transformations of the products, which are useful building blocks for the β-aminophosphonates, β-aminovinylphosphonates, and C-phosphorylated tetrazoles, indicate potential synthetic utility.