Biomimetic Synthesis of Moschamine-Related Indole Alkaloids via Iron-Catalyzed Selectively Oxidative Radical Coupling

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• 作者：Kangjiang Liang ; Jing Yang ; Xiaogang Tong ; Wenbin Shang ; Zhiqiang Pan ; Chengfeng Xia
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：March 18, 2016
• 年：2016
• 卷：18
• 期：6
• 页码：1474-1477
• 全文大小：359K
• ISSN：1523-7052

文摘

An iron-catalyzed oxidative radical coupling reaction was developed to selectively construct indolofuran or bisphenolic indole cores, which exist in two types of moschamine-related indole alkaloids. Both (+)-decursivine and 4,4″-bis(N-feruloyl)serotonin were biomimetically synthesized by using coupling reactions. The proposed reassignment of the structure of montamine as 4,4″-bis(N-feruloyl)serotonin was excluded.