Gold-Catalyzed [4+3]-Annulation of Oxabicyclic Benzenes with 2-Substituted Allylsilanes through Tandem Allylation and Cyclization

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• 作者：Yu-Chia Hsu ; Swarup Datta ; Chun-Ming Ting ; Rai-Shung Liu
• 刊名：Organic Letters
• 出版年：2008
• 出版时间：February 7, 2008
• 年：2008
• 卷：10
• 期：3
• 页码：521 - 524
• 全文大小：87K
• 年卷期：v.10,no.3(February 7, 2008)
• ISSN：1523-7052

文摘

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This work reports new gold-catalyzed [4 + 3]-annulations of oxacyclic benzenes with 2-substituted allylsilanes through tandem allylation andcyclization; on the basis of experimental observations, we propose a mechanism involving the opening of the oxacyclic ring by a PPh₃Au⁺-assisted S_N2-attack of allylsilanes.