Triterpene Cyclases from Oryza sativa L.: Cycloartenol, Parkeol and Achilleol B Synthases

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• 作者：Ryousuke Ito ; Kouya Mori ; Ippei Hashimoto ; Chiaki Nakano ; Tsutomu Sato ; Tsutomu Hoshino
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：May 20, 2011
• 年：2011
• 卷：13
• 期：10
• 页码：2678-2681
• 全文大小：750K
• 年卷期：v.13,no.10(May 20, 2011)
• ISSN：1523-7052

文摘

The gene products of AK121211, AK066327, and AK070534 from Oryza sativa encode cycloartenol, parkeol, and achilleol B synthases, respectively. Parkeol synthase is a unique enzyme that affords parkeol as a single product. Achilleol B synthase is the third seco-type triterpene cyclase identified to date, and triterpenes produced by this synthase include achilleol B (90%), tetracyclic (5.12%) and pentacyclic scaffolds (4.37%), and unidentified triterpenes (0.51%). The pathway for achilleol B biosynthesis is proposed.