The Structural Diversity of Phthalides from the Apiaceae

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• 作者：John J. Beck ; Shen-Chieh Chou
• 刊名：Journal of Natural Products
• 出版年：2007
• 出版时间：May 2007
• 年：2007
• 卷：70
• 期：5
• 页码：891 - 900
• 全文大小：211K
• 年卷期：v.70,no.5(May 2007)
• ISSN：1520-6025

文摘

Phthalides, and their corresponding dihydro and tetrahydro analogues, are components of several genera of the plantfamily Apiaceae. These taxa have been reported as exhibiting a wide range of bioactivities against experimentalmodels of several illnesses and physiological conditions, including microbial and viral infections, stroke, tuberculosis,and vasoconstriction. Many of these genera are purported to possess medicinal values, and of these several areconsidered to be traditional herbal medicines. This review provides an overview of the methods of investigation, thestructural diversity, and the bioactivity of phthalides, dihydrophthalides, tetrahydrophthalides, and dimers from plantsin the Apiaceae.