Zwitterionic Palladium Complexes: Room-Temperature Suzuki鈥揗iyaura Cross-Coupling of Sterically Hindered Substrates in an Aqueous Medium
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- 作者：Jhen-Yi Lee ; Dabalina Ghosh ; Jing-Yi Lee ; Shih-Sheng Wu ; Ching-Han Hu ; Shuang-De Liu ; Hon Man Lee
- 刊名：Organometallics
- 出版年：2014
- 出版时间：November 24, 2014
- 年：2014
- 卷：33
- 期：22
- 页码：6481-6492
- 全文大小：673K
- ISSN：1520-6041
文摘
A series of new imidazolium chlorides were straightforwardly prepared from the reactions between chloroacetone and imidazole derivatives. Deprotonation of the methylene proton next to the ketone group in these salts by pyridine led to the formation of a monodentate ligand that coordinated to palladium, readily forming zwitterionic anionic palladium pyridine complexes bearing a formal positive charge on the ligand ancillary. The pyridine ligand in the zwitterionic complexes can be facilely replaced by phosphine ligands. Seven of these new complexes were successfully characterized by X-ray crystallography. The zwitterionic phosphine complexes were highly efficient in catalyzing room-temperature Suzuki鈥揗iyaura reactions between sterically hindered aryl chlorides and arylboronic acids in an aqueous medium.