Chromatography and High-Resolution Mass Spectrometry for the Characterization of the Degradation Products of the Photodegradation of Amidosulfuron: An Analytical Approach

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• 作者：Mourad Harir ; Amina Chnirheb ; Basem Kanawati ; Mohammed El Azzouzi ; Philippe Schmitt-Kopplin
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2013
• 出版时间：June 5, 2013
• 年：2013
• 卷：61
• 期：22
• 页码：5271-5278
• 全文大小：537K
• 年卷期：v.61,no.22(June 5, 2013)
• ISSN：1520-5118

文摘

Simulated sunlight irradiation causing degradation of amidosulfuron, a pyrimidinylsulfonylurea herbicide, has been investigated in aqueous solution. The main degradation products were followed up by ultrahigh-pressure liquid chromatography with a UV detector (UHPLC-UV) and identified by combining ultrahigh-pressure liquid chromatography鈥搈ass spectrometry (UHPLC-MS) and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS). On the basis of the retrosynthetic analysis, the most identified degradation products were mainly due to the losses of methylsulfamic acid (CH₅NO₃S), sulfocarbamic acid (CH₃NO₅S), carbamic acid (CH₃NO₂), methyl(methylsulfonyl)sulfamic acid (C₂H₇NO₅S₂), N-methylmethanesulfonamide (C₂H₇NO₂S), and sulfonic acid (H₂SO₄) molecules. Accordingly, O and S-demethylation as well as hydroxylation processes were also observed. Sum formulas of the main degradation products were assigned, and a mechanical pathway is proposed.

Keywords:

amidosulfuron; degradation products; UHPLC-UV; UHPLC-MS; FT-ICR-MS