A Catalyst-Free Synthesis of Phosphinic Amides Using O-Benzoylhydroxylamines
详细信息 查看全文
- 作者：Rui Zhu ; Chongqing Pan ; Zhenhua Gu
- 刊名：Organic Letters
- 出版年：2015
- 出版时间：December 4, 2015
- 年：2015
- 卷：17
- 期：23
- 页码：5862-5865
- 全文大小：404K
- ISSN：1523-7052
文摘
A practical approach for the synthesis of phosphinic amides via the coupling of secondary phosphine oxides (SPOs) with O-benzoylhydroxylamines has been reported. Simply heating the mixture of SPOs and O-benzoylhydroxylamines in the presence of K2CO3 gave the phosphinic amides in moderate to excellent yields under an open air system. This method provides a practical and catalyst-free method for the synthesis of various synthetically valuable phosphinic amides.