A Converter from the Systems Biology Markup Language to the Synthetic Biology Open Language
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- 作者：Tramy Nguyen ; Nicholas Roehner ; Zach Zundel ; Chris J. Myers
- 刊名：ACS Synthetic Biology
- 出版年：2016
- 出版时间：June 17, 2016
- 年：2016
- 卷：5
- 期：6
- 页码：479-486
- 全文大小：373K
- 年卷期：0
- ISSN：2161-5063
文摘
Standards are important to synthetic biology because they enable exchange and reproducibility of genetic designs. This paper describes a procedure for converting between two standards: the Systems Biology Markup Language (SBML) and the Synthetic Biology Open Language (SBOL). SBML is a standard for behavioral models of biological systems at the molecular level. SBOL describes structural and basic qualitative behavioral aspects of a biological design. Converting SBML to SBOL enables a consistent connection between behavioral and structural information for a biological design. The conversion process described in this paper leverages Systems Biology Ontology (SBO) annotations to enable inference of a designs qualitative function.