Effects of Co-solvents on Reactions Run under Micellar Catalysis Conditions

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• 作者：Christopher M. Gabriel ; Nicholas R. Lee ; Florence Bigorne ; Piyatida Klumphu ; Michael Parmentier ; Fabrice Gallou ; Bruce H. Lipshutz
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：January 6, 2017
• 年：2017
• 卷：19
• 期：1
• 页码：194-197
• 全文大小：376K
• ISSN：1523-7052

文摘

The impact of varying percentages of an organic solvent added to reactions run in aqueous nanomicelles as the reaction medium has been investigated. Issues such as rates of reaction, percent conversion, and yield, as well as various practical aspects (e.g., effect on stirring, etc.), are discussed, leading to an operationally simple method for the general improvement of potentially problematic systems across a broad range of reaction types, in particular for reactions run at scale.