C-C Bond-Forming Reactions via Pd-Mediated Decarboxylative -Imino Anion Generation

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• 作者：Andrew A. Yeagley ; Jason J. Chruma
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：July 19, 2007
• 年：2007
• 卷：9
• 期：15
• 页码：2879 - 2882
• 全文大小：103K
• 年卷期：v.9,no.15(July 19, 2007)
• ISSN：1523-7052

文摘

-Imino anions are generated under neutral reaction conditions via a Pd-mediated decarboxylation of allyl diphenylglycinate imines withconcomitant formation of a -allylpalladium species. The resulting delocalized anion can attack the -allyl-Pd(II) species or be intercepted byaldehydes to afford homoallylic amines or protected 1,2-amino alcohols, respectively.