文摘
Seven new compounds, including a eupodienone-type lignan (1), a dibenzocyclooctadiene-type lignan (2), three tetrahydrofuran-type lignans (3鈥?b>5), and two 1-phenylbutyl benzoates (6, 7), together with six known compounds, were isolated from the mature carpels of Manglietiastrum sinicum. The structures of new compounds 1鈥?b>7 were defined by spectroscopic techniques, and the absolute configuration of manglisin A (1) was determined by X-ray crystallography. Compounds 1鈥?b>4 exhibited moderate antimicrobial activities (MIC values: 0.016鈥?.14 渭M) against Staphylococcus aureus, MRSA 82#, MRSA 92#, MRSA 98#, and MRSA 331#. Compounds 2 and 3 showed weak cytotoxic activity against five human tumor cell lines.