Facile One-Pot Preparation of Chitosan/Calcium Pyrophosphate Hybrid Microflowers

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• 作者：Xiaoli Wang ; Jiafu Shi ; Zheng Li ; Shaohua Zhang ; Hong Wu ; Zhongyi Jiang ; Chen Yang ; Chunyong Tian
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2014
• 出版时间：August 27, 2014
• 年：2014
• 卷：6
• 期：16
• 页码：14522-14532
• 全文大小：754K
• ISSN：1944-8252

文摘

Flower-like chitosan/calcium pyrophosphate hybrid microparticles (microflowers) are prepared using a facile one-pot approach by combining ionotropic gelation with biomimetic mineralization. Chitosan鈥搕ripolyphosphate (CS-TPP) nanocomplexes are first synthesized through ionotropic gelation; meanwhile, excess TPP is partly hydrolyzed into pyrophosphate ions (P₂O₇4鈥?/sup>). Upon addition of CaCl₂, CS-TPP nanocomplexes serve as a versatile template, inducing in situ mineralization of Ca₂P₂O₇ and directing its growth and assembly into microflowers. The whole preparation process can be completed within half an hour. The as-prepared microflowers are composed of 23.0% CS-TPP nanocomplexes and 77.0% Ca₂P₂O₇ crystals. Mesopores (3.7 and 11.2 nm) and macropores coexist in the microflowers, indicating porous and hierarchical structures. The microflowers exhibit high efficiency in dye adsorption and enzymatic catalysis. Specifically, a high adsorption capacity of 520 mg g^鈥? for Congo red is achieved. And the immobilized enzyme retains about 85% catalytic activity compared with that of the free enzyme. The facile one-pot preparation process ensures the broad applications of the porous hybrid microflowers.

Keywords:

microflowers; chitosan; calcium pyrophosphate; mineralization; dye adsorption; enzyme immobilization