The First Sequential Reaction Promoted by Manganese: Complete Stereoselective Synthesis of (E)-,mg src="http://pubs.acs.org/images

详细信息    查看全文

• 作者：José ; M. Concell&oacute ; n ; Humberto Rodrí ; guez-Solla ; Pamela Dí ; az ; Ricardo Llavona
• 刊名：Journal of Organic Chemistry
• 出版年：2007
• 出版时间：June 8, 2007
• 年：2007
• 卷：72
• 期：12
• 页码：4396 - 4400
• 全文大小：79K
• 年卷期：v.72,no.12(June 8, 2007)
• ISSN：1520-6904

文摘

MG SRC="/isubscribe/journals/joceah/72/i12/figures/jo070209wn00001.gif" ALIGN="left" HSPACE=5>

mages/gifchars/alpha.gif" BORDER=0>,mages/gifchars/beta2.gif" BORDER=0 ALIGN="middle">-Unsaturated esters were obtained with complete control of stereoselectivity utilizing a sequentialreaction of dichloroesters with a variety of aldehydes, promoted by active manganese. This methodologyis generally applicable, and the C-C double bond can be di- or trisubstituted. A mechanism based on asuccessive aldol-type reaction/mages/gifchars/beta2.gif" BORDER=0 ALIGN="middle">-elimination is proposed to explain these results.