Zoaramine, a Zoanthamine-like Alkaloid with a New Skeleton

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• 作者：Francisco Cen-Pacheco ; Manuel Norte ; Jos茅 J. Fern谩ndez ; Antonio Hern谩ndez Daranas
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：June 6, 2014
• 年：2014
• 卷：16
• 期：11
• 页码：2880-2883
• 全文大小：209K
• 年卷期：v.16,no.11(June 6, 2014)
• ISSN：1523-7052

文摘

Chemical investigation of an Atlantic variety of Zoanthus sp. led to the isolation of two new metabolites, zoaramine and zoarenone. Their structures were deduced by the use of NMR spectroscopy and computational calculation of ¹H and ¹³C chemical shifts. The core of these novel compounds resembles the structure of norzoanthamine alkaloids, and their isolation represents an important step toward a better understanding of the biogenetic origin of this group of antiosteoporotic molecules.