Metal-Free C–H Functionalization of Alkanes by Aryldiazoacetates

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• 作者：Cecilia Tortoreto ; Daniel Rackl ; Huw M. L. Davies
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：February 17, 2017
• 年：2017
• 卷：19
• 期：4
• 页码：770-773
• 全文大小：431K
• ISSN：1523-7052

文摘

Thermally induced reactions of donor/acceptor diazo compounds generate carbene intermediates capable of C–H functionalization reactions of alkanes. A variety of C–H insertion products were obtained in moderate to good yields and in certain cases with good site selectivity, favoring the functionalization of the more highly substituted C–H bond.