Rhodium-Catalyzed Enantioselective Hydrogenation of 尾-Acylamino Nitroolefins: A New Approach to Chiral 尾-Amino Nitroalkanes
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- 作者：Ming Zhou ; Dejun Dong ; Baolin Zhu ; Huiling Geng ; Yan Wang ; Xumu Zhang
- 刊名：Organic Letters
- 出版年：2013
- 出版时间：November 1, 2013
- 年：2013
- 卷：15
- 期：21
- 页码：5524-5527
- 全文大小：257K
- 年卷期：v.15,no.21(November 1, 2013)
- ISSN：1523-7052
文摘
An efficient and highly enantioselective catalytic asymmetric hydrogenation of 尾-acylamino nitroolefins has been realized by using Rh-TangPhos as the catalyst. A series of 尾-amino nitroalkane products, which are versatile intermediates in organic synthesis, were obtained with high yield and good enantioselectivity.