Chiral Amido Alkyl Rare Earth Complexes: A New Family of Asymmetric Intramolecular Hydroamination Catalysts

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• 作者：Isabelle Aillaud ; Dmitrii Lyubov ; Jacqueline Collin ; Ré ; gis Guillot ; Jé ; rô ; me Hannedouche ; Emmanuelle Schulz ; Alexander Trifonov
• 刊名：Organometallics
• 出版年：2008
• 出版时间：November 24, 2008
• 年：2008
• 卷：27
• 期：22
• 页码：5929-5936
• 全文大小：277K
• 年卷期：v.27,no.22(November 24, 2008)
• ISSN：1520-6041

文摘

New chiral binaphthylamido alkyl ate and neutral yttrium and ytterbium complexes have been synthesized and characterized. X-ray structures have been obtained for ate alkyl complexes [(R)-C₂₀H₁₂(NC₅H₉)₂]Y[(μ-Me)₂Li(THF)₂(μ-Me)Li(THF)] and [(R)-C₂₀H₁₂(NC₅H₉)₂]Ln[(μ-Me)₂Li(TMEDA)(μ-Me)Li(OEt₂)] (Ln = Y, Yb) and for the neutral complex [(R)-C₂₀H₁₂(NC₅H₉)₂]YCH₂SiMe₃(DME). Both types of complexes can be easily prepared in a one-pot procedure starting from yttrium and ytterbium chlorides and used in situ. They proved to be very efficient catalysts for enantioselective intramolecular hydroamination of aminopentenes or aminohexene at room temperature with enantiomeric excesses up to 83%.