Proton Abstraction Mechanism for the Palladium-Catalyzed Intramolecular Arylation

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• 作者：Domingo Garc&iacute ; a-Cuadrado ; Ataualpa A. C. Braga ; Feliu Maseras ; and Antonio M. Echavarren
• 刊名：Journal of the American Chemical Society
• 出版年：2006
• 出版时间：February 1, 2006
• 年：2006
• 卷：128
• 期：4
• 页码：1066 - 1067
• 全文大小：68K
• 年卷期：v.128,no.4(February 1, 2006)
• ISSN：1520-5126

文摘

Under the usual conditions, the Pd-catalyzed arylation does not involve an electrophilic aromatic substitution reaction. On the basis of DFT calculations, we propose a mechanism for the Pd-catalyzed arylation that involves a proton abstraction by a carbonate or related ligand and that provides a satisfactory explanation for the experimental data.