Ilelic Acids A and B, Two Unusual Triterpenes with a Seven-Membered Ring from Ilex latifolia
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- 作者：Cun-Qin Wang ; Lei Wang ; Chun-Lin Fan ; Dong-Mei Zhang ; Xiao-Jun Huang ; Ren-Wang Jiang ; Liang-Liang Bai ; Jun-Min Shi ; Ying Wang ; Wen-Cai Ye
- 刊名：Organic Letters
- 出版年：2012
- 出版时间：August 17, 2012
- 年：2012
- 卷：14
- 期：16
- 页码：4102-4105
- 全文大小：297K
- 年卷期：v.14,no.16(August 17, 2012)
- ISSN：1523-7052
文摘
Two unusual triterpenes, ilelic acids A (1) and B (2), together with their biosynthetic related compounds ilelic acids C (3) and D (4) were isolated from the leaves of Ilex latifolia. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher鈥檚 method. The plausible biogenetic pathway of 1 and 2 is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells.