Rhodium Catalyzed Direct Arylation of 伪-Diazoimines
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- 作者：Dongari Yadagiri ; Pazhamalai Anbarasan
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：May 2, 2014
- 年：2014
- 卷：16
- 期：9
- 页码：2510-2513
- 全文大小：334K
- 年卷期：v.16,no.9(May 2, 2014)
- ISSN：1523-7052
文摘
An efficient rhodium catalyzed direct arylation of 伪-diazoimines, generated from readily accessible 1,2,3-triazole, has been accomplished for the synthesis of 2,2-diaryl enamides. The reaction involves the chemo- and regioselective insertion of rhodium azavinyl carbene into aromatic C(sp2)鈥揌 bonds. Utility of the developed methodology was demonstrated in the synthesis of indole and tetrahydroisoquinoline frameworks.