A Strategy for Highly Selective Detection and Imaging of Hypochlorite Using Selenoxide Elimination

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• 作者：Guoping Li ; Dongjian Zhu ; Qing Liu ; Lin Xue ; Hua Jiang
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：April 19, 2013
• 年：2013
• 卷：15
• 期：8
• 页码：2002-2005
• 全文大小：243K
• 年卷期：v.15,no.8(April 19, 2013)
• ISSN：1523-7052

文摘

A new strategy for HOCl-specific fluorescent probes has been reported based on a selenoxide elimination reaction. Probes CM1 and CM2 were synthesized as the first fluorescent probes containing an arylseleno moiety for hypochlorite according to this strategy. Both probes displayed excellent properties, including high selectivity and sensitivity, fast response, and pH independency toward hypochlorite in vitro and vivo.