Bacterial Spore Detection by [Tb3+(macrocycle)(dipicolinate)] Luminescence

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• 作者：Morgan L. Cable ; James P. Kirby ; Karn Sorasaenee ; Harry B. Gray ; Adrian Ponce
• 刊名：Journal of the American Chemical Society
• 出版年：2007
• 出版时间：February 14, 2007
• 年：2007
• 卷：129
• 期：6
• 页码：1474 - 1475
• 全文大小：77K
• 年卷期：v.129,no.6(February 14, 2007)
• ISSN：1520-5126

文摘

Dipicolinic acid (DPA) is a unique constituent of bacterial spores, a dormant form of Bacillus and Clostridium, which can be detected using DPA-triggered Tb³⁺ luminescence. [Tb(DO2A)]⁺ improves the sensitivity of bacterial spore detection over Tb³⁺(aq) owing to the exclusion of coordinated water molecules and represents the first step toward construction of a DPA receptor site with enhanced binding selectivity. The title ternary [Tb(DO2A)(DPA)]^- complex was structurally characterized and features two DO2A-DPA interligand hydrogen interactions that stabilize the complex.