Effect of Diets Based on Foods from Conventional versus Organic Production on Intake and Excretion of Flavonoids and Markers of Antioxidative Defense in Humans

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• 作者：Lisbeth Grinder-Pedersen ; Salka E. Rasmussen ; Susanne Bü ; gel ; Lars V. J//pubs.acs.org/images/gifchars/oslash.gif" border="0">rgensen ; Lars O. Dragsted ; Vagn Gundersen ; and Brittmari
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2003
• 出版时间：September 10, 2003
• 年：2003
• 卷：51
• 期：19
• 页码：5671 - 5676
• 全文大小：62K
• 年卷期：v.51,no.19(September 10, 2003)
• ISSN：1520-5118

文摘

Different food production methods may result in differences in the content of secondary metabolitessuch as polyphenolic compounds. The present study compared conventionally (CPD) and organicallyproduced (OPD) diets in a human crossover intervention study (n = 16) with respect to the intakeand excretion of five selected flavonoids and effect on markers of oxidative defense. The urinaryexcretion of quercetin and kaempferol was higher after 22 days of intake of the OPD when comparedto the CPD (P < 0.05). The excretions of flavonoids in urine as a percentage of intake (0.6-4%)were similar after both interventions. Most markers of antioxidative defense did not differ betweenthe diets, but intake of OPD resulted in an increased protein oxidation and a decreased total plasmaantioxidant capacity compared to baseline (P < 0.05). Some varietal difference was seen in the study,and because selection of more resistant varieties is of central importance to organic farming, it cannotbe excluded that the observed effects originate from these differences. The food production methodaffected the content of the major flavonoid, quercetin, in foods and also affected urinary flavonoidsand markers of oxidation in humans.Keywords: Flavonoids; humans; organic food production; conventional food production; urinaryexcretion; antioxidative defense