Photocontrolled Binding and Binding-Controlled Photochromism within Anthracene-Modified DNA

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• 作者：Jack Manchester ; Dario M. Bassani ; Jean-Louis H. A. Duprey ; Luciana Giordano ; Joseph S. Vyle ; Zheng-yun Zhao ; James H. R. Tucker
• 刊名：The Journal of the American Chemical Society
• 出版年：2012
• 出版时间：July 4, 2012
• 年：2012
• 卷：134
• 期：26
• 页码：10791-10794
• 全文大小：229K
• 年卷期：v.134,no.26(July 4, 2012)
• ISSN：1520-5126

文摘

Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.