Cyclometalation of Secondary Benzyl Amines by Ruthenium(II) Complexes
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- 作者：Jean-Baptiste Sortais ; Nicolas Pannetier ; Nicolas Clé ; ment ; Laurent Barloy ; Claude Sirlin ; Michel Pfeffer ; Nathalie Kyritsakas
- 刊名：Organometallics
- 出版年：2007
- 出版时间：April 9, 2007
- 年：2007
- 卷：26
- 期：8
- 页码：1868 - 1874
- 全文大小：150K
- 年卷期：v.26,no.8(April 9, 2007)
- ISSN：1520-6041
文摘
The cyclometalation of chiral secondary amines through ortho-metalation of an aryl group occurredreadily with [(
6-benzene)RuCl2]2 in acetonitrile. Reasonable to good yields of the expected cationicproducts of the form [(6-benzene)Ru(N-C)(NCMe)](PF6), in which N-C represents the cyclometalatedligands, were obtained with bis-(R)-phenylethylamine, bis-(R)-1-naphthylethylamine, and (2R,5R)-2,5-diphenylpyrrolidine. Variable proportions of the expected four diastereoisomers were found according toNMR studies. The stereochemistry of complexes was investigated by 2D NMR in solution and by X-raydiffraction of single crystals. The (S) configuration at the metal was generally associated with a 
conformation of the metallacycle, and conversely, the (R) configuration with the 
conformation.
6-benzene)RuCl2]2 in acetonitrile. Reasonable to good yields of the expected cationicproducts of the form [(6-benzene)Ru(N-C)(NCMe)](PF6), in which N-C represents the cyclometalatedligands, were obtained with bis-(R)-phenylethylamine, bis-(R)-1-naphthylethylamine, and (2R,5R)-2,5-diphenylpyrrolidine. Variable proportions of the expected four diastereoisomers were found according toNMR studies. The stereochemistry of complexes was investigated by 2D NMR in solution and by X-raydiffraction of single crystals. The (S) configuration at the metal was generally associated with a conformation of the metallacycle, and conversely, the (R) configuration with the conformation.