Nitrogen Kinetic Isotope Effects for the Monoamine Oxidase B-Catalyzed Oxidation of Benzylamine and (1,1-2H2)Benzylamine: Nitrogen Rehybridization and CH Bond Cleavage Are Not Co
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- 作者：Susanna MacMillar ; Dale E. Edmondson ; Olle Matsson
- 刊名：Journal of the American Chemical Society
- 出版年：2011
- 出版时间：August 17, 2011
- 年：2011
- 卷：133
- 期：32
- 页码：12319-12321
- 全文大小：698K
- 年卷期：v.133,no.32(August 17, 2011)
- ISSN：1520-5126
文摘
Nitrogen kinetic isotope effects for the oxidation of benzylamine and (1,1-2H2)benzylamine by recombinant human monoamine oxidase B show that cleavage of the CH bond is not concerted with rehybridization of the nitrogen atom.