Synthesis of Tetrazole-Fused Glycosides by a Tandem Fragmentation鈥揅yclization Reaction

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• 作者：Nieves R. Paz ; Andr茅s G. Santana ; Cosme G. Francisco ; Ernesto Su谩rez ; Concepci贸n C. Gonz谩lez
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：July 6, 2012
• 年：2012
• 卷：14
• 期：13
• 页码：3388-3391
• 全文大小：268K
• 年卷期：v.14,no.13(July 6, 2012)
• ISSN：1523-7052

文摘

The fragmentation of anomeric alkoxyl radicals (ARF) and the subsequent intramolecular cyclization promoted by hypervalent iodine reagents provide an excellent method for the synthesis of tetrazolo-sugars. This new reaction offers additional advantages for the synthesis of these compounds, including the ready availability of the starting materials, experimental simplicity, mild conditions, and good yields.