Facile and Rapid Access to Glyconanocapsules by CuAAC Interfacial Polyaddition in Miniemulsion Conditions
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- 作者：R茅mi Roux ; Ludovic Sallet ; Pierre Alcouffe ; St茅phane Chambert ; Nathalie Sintes-Zydowicz ; Etienne Fleury ; Julien Bernard
- 刊名：ACS Macro Letters
- 出版年：2012
- 出版时间：August 21, 2012
- 年：2012
- 卷：1
- 期：8
- 页码：1074-1078
- 全文大小：297K
- 年卷期：v.1,no.8(August 21, 2012)
- ISSN：2161-1653
文摘
Glyconanocapsules with a biocompatible oily core have been successfully prepared by copper(I)-catalyzed azide鈥揳lkyne cycloaddition (CuAAC) interfacial step growth polymerization between 6,6鈥?diazido-6,6鈥?dideoxysucrose and bis(propargyloxy)butane in oil-in-water miniemulsion conditions. Optimization of the interfacial polymerization process in dispersed medium afforded the rapid and reproducible preparation of stable monodispersed glyconanocapsules having a diameter around 200 nm.