Scalarane-Based Sesterterpenoid RCE-Protease Inhibitors Isolated from the Indonesian Marine Sponge Carteriospongia foliascens
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- 作者：David E. Williams ; Irwin Hollander ; Larry Feldberg ; Eileen Frommer ; Robert Mallon ; Akbar Tahir ; Rob van Soest ; Raymond J. Andersen
- 刊名：Journal of Natural Products
- 出版年：2009
- 出版时间：June 26, 2009
- 年：2009
- 卷：72
- 期：6
- 页码：1106-1109
- 全文大小：108K
- 年卷期：v.72,no.6(June 26, 2009)
- ISSN：1520-6025
文摘
Two new 20,24-bishomo-25-norscalaranes, compounds 1 and 2, and two new and two known 20,24-bishomoscalaranes, compounds 3−6, have been isolated from the Indonesian marine sponge Carteriospongia foliascens. The structures of 1−6 were determined by spectroscopic analysis. Compounds 1 and 3−6 inhibit RCE-protease activity.