Rhodium-Catalyzed Intermolecular [2 + 2] Cycloaddition of Terminal Alkynes with Electron-Deficient Alkenes

详细信息    查看全文

• 作者：Kazunori Sakai ; Takuya Kochi ; Fumitoshi Kakiuchi
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：March 1, 2013
• 年：2013
• 卷：15
• 期：5
• 页码：1024-1027
• 全文大小：241K
• 年卷期：v.15,no.5(March 1, 2013)
• ISSN：1523-7052

文摘

The first catalytic intermolecular [2 + 2] cycloaddition of terminal alkynes with electron-deficient alkenes is reported. The reaction proceeds with an 8-quinolinolato rhodium/phosphine catalyst system to give cyclobutenes from various substrates having polar functional groups in high yields with complete regioselectivity.