Ingestion of Water-Soluble Soybean Fiber Prevents Osteopenia and Hypercholesterolemia Induced by Ovariectomy in Rats

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• 作者：Rieko Mitamura ; Hiroshi Hara ; Yoritaka Aoyama ; Taro Takahashi ; and Hitoshi Furuta
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2003
• 出版时间：February 12, 2003
• 年：2003
• 卷：51
• 期：4
• 页码：1085 - 1089
• 全文大小：60K
• 年卷期：v.51,no.4(February 12, 2003)
• ISSN：1520-5118

文摘

This study examined the effects of feeding water-soluble soybean fiber (WSSF), a highly fermentabledietary fiber with low viscosity, on intestinal calcium (Ca) absorption, bone mineral content, and serumtotal cholesterol levels using female Sprague-Dawley rats (5 weeks old) with or without ovariectomy(OVX). The rats in each group were fed a WSSF (50 g/kg of diet) or WSSF-free diet for 4 weeks. Caabsorption was higher in OVX rats fed the WSSF diet than in OVX rats fed the WSSF-free diet.Femoral Ca content in both sham and OVX rats fed the WSSF diet was higher than that in rats fedthe WSSF-free diet. The serum total cholesterol levels were elevated after OVX compared with thatin the sham rats, and this elevation was prevented by the WSSF diet. In conclusion, ingestion ofWSSF prevented osteopenia and hypercholesterolemia induced by ovariectomy in rats.Keywords: Water-soluble soybean fiber; osteopenia; hypercholesterolemia; ovariectomy; rats