Selective Carbonylation Routes to Thiocarbamates. An Alternative to Phosgene

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• 作者：William D. Jones ; Kelly A. Reynolds ; Caroline K. Sperry ; Rene J. Lachicotte ; Stephen A. Godleski ; and Ronald R. Valente
• 刊名：Organometallics
• 出版年：2000
• 出版时间：May 1, 2000
• 年：2000
• 卷：19
• 期：9
• 页码：1661 - 1669
• 全文大小：332K
• 年卷期：v.19,no.9(May 1, 2000)
• ISSN：1520-6041

文摘

A new route for the synthesis of thiocarbamates using a transition metal complex and COas a replacement for phosgene has been discovered. The complex (PPh₃)₂PdCl₂ reacts withN-benzylmethylamine, 4-chlorobenzenethiol, and CO to selectively generate a thiocarbamate.Kinetic studies and the isolation of several intermediates in this reaction allow for theproposal of a mechanistic scheme.