Fe3O4 Nanoparticle-Supported Copper(I) Pybox Catalyst: Magnetically Recoverable Catalyst for Enantioselective Direct-Addition of Terminal Alkynes to Imines

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• 作者：Tieqiang Zeng ; Luo Yang ; Reuben Hudson ; Gonghua Song ; Audrey R. Moores ; Chao-Jun Li
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：February 4, 2011
• 年：2011
• 卷：13
• 期：3
• 页码：442-445
• 全文大小：211K
• 年卷期：v.13,no.3(February 4, 2011)
• ISSN：1523-7052

文摘

An Fe₃O₄ nanoparticle-supported copper(I) pybox catalyst, which exhibits excellent reactivity and yields products with good enantioselectivity, was developed. As a proof of concept, six optically active propargyl amines were obtained in excellent yields. The catalyst can be magnetically removed and recycled easily six times without a decrease in activity or enantioselectivity.