Efficient Microwave-Assisted Pd-Catalyzed Hydroxylation of Aryl Chlorides in the Presence of Carbonate

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• 作者：Chao-Wu Yu ; Grace S. Chen ; Chen-Wei Huang ; Ji-Wang Chern
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：July 20, 2012
• 年：2012
• 卷：14
• 期：14
• 页码：3688-3691
• 全文大小：223K
• 年卷期：v.14,no.14(July 20, 2012)
• ISSN：1523-7052

文摘

An efficient microwave-assisted, palladium-catalyzed hydroxylation of aryl chlorides in the presence of a weak base carbonate was developed, which rapidly converts aryl and heteroaryl chlorides to phenols, and can be used when the aryl chloride is functionalized with a ketone, aldehyde, ester, nitrile, or amide.