Copper Complexes as Bioinspired Models for Lytic Polysaccharide Monooxygenases
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- 作者：Alda Lisa Concia ; Maria Rosa Beccia ; Maylis Orio ; Francine Terra Ferre ; Marciela Scarpellini ; Frédéric Biaso ; Bruno Guigliarelli ; Marius Réglier ; A. Jalila Simaan
- 刊名：Inorganic Chemistry
- 出版年：2017
- 出版时间：February 6, 2017
- 年：2017
- 卷：56
- 期：3
- 页码：1023-1026
- 全文大小：284K
- ISSN：1520-510X
文摘
We report here two copper complexes as first functional models for lytic polysaccharide monooxygenases, mononuclear copper-containing enzymes involved in recalcitrant polysaccharide breakdown. These complexes feature structural and spectroscopic properties similar to those of the enzyme. In addition, they catalyze oxidative cleavage of the model substrate p-nitrophenyl-β-d-glucopyranoside. More importantly, a particularly stable copper(II) hydroperoxide intermediate is detected in the reaction conditions.