Br酶nsted Acid Catalyzed Benzylic C鈥揌 Bond Functionalization of Azaarenes: Nucleophilic Addition to Nitroso Compounds

详细信息    查看全文

• 作者：Xu Gao ; Feng Zhang ; Guojun Deng ; Luo Yang
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：July 18, 2014
• 年：2014
• 卷：16
• 期：14
• 页码：3664-3667
• 全文大小：334K
• ISSN：1523-7052

文摘

A practical Br酶nsted acid promoted benzylic C鈥揌 functionalization of 2-alkylazaarenes and nucleophilic addition to nitroso compounds was developed under mild conditions. Switched by Br酶nsted acids, this method can afford azaarene-2-aldimines, azaarene-2-carbaldehyde, or azaarene-2-oximes selectively. No metal, base, oxidant, or other additives were required.