Linear Free-Energy Relationship Analysis of a Catalytic Desymmetrization Reaction of a Diarylmethane-bis(phenol)

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• 作者：Jeffrey L. Gustafson ; Matthew S. Sigman ; Scott J. Miller
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：June 18, 2010
• 年：2010
• 卷：12
• 期：12
• 页码：2794-2797
• 全文大小：196K
• 年卷期：v.12,no.12(June 18, 2010)
• ISSN：1523-7052

文摘

Linear free-energy relationships have been found for enantioselectivity and various steric parameters in an enantioselective desymmetrization of symmetrical bis(phenol) substrates. The potential origin of this observation and the role of different steric parameters are discussed.