A Mesoporous Indium Metal–Organic Framework: Remarkable Advances in Catalytic Activity for Strecker Reaction of Ketones
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- 作者：Daniel Reinares-Fisac ; Lina María Aguirre-Díaz ; Marta Iglesias ; Natalia Snejko ; Enrique Gutiérrez-Puebla ; M. Ángeles Monge ; Felipe Gándara
- 刊名：Journal of the American Chemical Society
- 出版年：2016
- 出版时间：July 27, 2016
- 年：2016
- 卷：138
- 期：29
- 页码：9089-9092
- 全文大小：348K
- 年卷期：0
- ISSN：1520-5126
文摘
With the aim of developing new highly porous, heterogeneous Lewis acid catalysts for multicomponent reactions, a new mesoporous metal–organic framework, InPF-110 ([In3O(btb)2(HCOO)(L)], (H3btb = 1,3,5-tris(4-carboxyphenyl)benzene acid, L = methanol, water, or ethanol), has been prepared with indium as the metal center. It exhibits a Langmuir surface area of 1470 m2 g–1, and its structure consists of hexagonal pores with a 2.8 nm aperture, which allows the diffusion of multiple substrates. This material presents a large density of active metal sites resulting in outstanding catalytic activity in the formation of substituted α-aminonitriles through the one-pot Strecker reaction of ketones. In this respect, InPF-110 stands out compared to other catalysts for this reaction due to the small catalyst loadings required, and without the need for heat or solvents. Furthermore, X-ray single crystal diffraction studies clearly show the framework–substrate interaction through coordination to the accessible indium sites.