Highly Sensitive and Selective Fluorescent Probe for Ascorbic Acid with a Broad Detection Range through Dual-Quenching and Bimodal Action of Nitronyl-Nitroxide
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- 作者：Haerim Nam ; Ji Eon Kwon ; Min-Woo Choi ; Jangwon Seo ; Seunghoon Shin ; Sehoon Kim ; Soo Young Park
- 刊名：ACS Sensor
- 出版年：2016
- 出版时间：April 22, 2016
- 年：2016
- 卷：1
- 期：4
- 页码：392-398
- 全文大小：538K
- ISSN：2379-3694
文摘
A novel nitronyl-nitroxide derivative for highly sensitive and selective detection of ascorbic acid (AA) is reported. The probe showed 260-fold fluorescence turn-on and diminished electron spin resonance (ESR) signal upon AA addition. The probe could detect AA over a broad concentration range from 1 μM to 2 mM and excellent selectivity over various antioxidants and acids through a combination of fluorescence and ESR responses, which originated from the dual-reactiveness of dual-quenching group nitronyl-nitroxide. We successfully demonstrated practical application potential of the probe by preparing nanoparticles and sensor papers and determining AA concentration in real samples including vitamin drinks and orange juices.