One Step Cascade Synthesis of 4,5-Disubstituted-1,2,3-(NH)-Triazoles

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• 作者：Sujata Sengupta ; Haifeng Duan ; Weibing Lu ; Jeffrey L. Petersen ; Xiaodong Shi
• 刊名：Organic Letters
• 出版年：2008
• 出版时间：April 3, 2008
• 年：2008
• 卷：10
• 期：7
• 页码：1493 - 1496
• 全文大小：79K
• 年卷期：v.10,no.7(April 3, 2008)
• ISSN：1523-7052

文摘

A Lewis base-catalyzed three-component cascade reaction was developed for the synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles. More than25 new (NH)-triazoles were prepared in good to excellent yields under mild conditions. The availability of the C-4 vinyl group allows easyconversion into other triazole derivatives.