Gateway Reactions to Diverse, Polyfunctional Monolayer-Protected Gold Clusters
详细信息 查看全文
- 作者：Allen C. Templeton ; Michael J. Hostetler ; Emily K. Warmoth ; Shaowei Chen ; Chris M. Hartshorn ; Vijay M. Krishnamurthy ; Malcolm D. E. Forbes ; and Royce W. Murray
- 刊名：Journal of the American Chemical Society
- 出版年：1998
- 出版时间：May 20, 1998
- 年：1998
- 卷：120
- 期：19
- 页码：4845 - 4849
- 全文大小：57K
- 年卷期：v.120,no.19(May 20, 1998)
- ISSN：1520-5126
文摘
Amide and ester coupling reactions of 
-functionalizedmonolayer-protected gold cluster molecules(MPCs) are an exceptionally efficient avenue to a diverse variety ofpolyfunctionalized MPCs starting from asmall subset of -functionalized materials. In this paper,coupling reactions have been employed to produce13 MPCs bearing multiple copies of a diverse variety of structuralgroups. Detailed features of three of the13 polyfunctionalized products are highlighted: (a)stepwise coupling and deprotection reactions result in anMPC surrounded by ca. eight pendant tripeptides, (b) apreliminary Steady-State Electron ParamagneticResonance (SSEPR) experiment is described for MPCs bearing multiplespin labels (ca. 13/cluster), and (c) apolyelectron electrochemical reaction is described for an MPC bearingmultiple (ca. 7/cluster) coupledphenothiazine derivatives. The coupling reactions substantiallyexpand the available diversity of MPCs aspolyfunctionalized chemical reagents platformed on a nanometer-sizedcentral core.
-functionalizedmonolayer-protected gold cluster molecules(MPCs) are an exceptionally efficient avenue to a diverse variety ofpolyfunctionalized MPCs starting from asmall subset of -functionalized materials. In this paper,coupling reactions have been employed to produce13 MPCs bearing multiple copies of a diverse variety of structuralgroups. Detailed features of three of the13 polyfunctionalized products are highlighted: (a)stepwise coupling and deprotection reactions result in anMPC surrounded by ca. eight pendant tripeptides, (b) apreliminary Steady-State Electron ParamagneticResonance (SSEPR) experiment is described for MPCs bearing multiplespin labels (ca. 13/cluster), and (c) apolyelectron electrochemical reaction is described for an MPC bearingmultiple (ca. 7/cluster) coupledphenothiazine derivatives. The coupling reactions substantiallyexpand the available diversity of MPCs aspolyfunctionalized chemical reagents platformed on a nanometer-sizedcentral core.