Organolutetium-Mediated Dearomatization and Functionalization of Pyrimidine Rings

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• 作者：Kevin R. D. Johnson ; Paul G. Hayes
• 刊名：Organometallics
• 出版年：2013
• 出版时间：August 12, 2013
• 年：2013
• 卷：32
• 期：15
• 页码：4046-4049
• 全文大小：255K
• 年卷期：v.32,no.15(August 12, 2013)
• ISSN：1520-6041

文摘

The synthesis of a pentadentate NNNNN bis(phosphinimine)carbazole pincer ligand bearing two pyrimidine N-aryl rings is reported. A dialkyl lutetium complex of the ligand, prepared by alkane elimination with Lu(CH₂SiMe₃)₃(THF)₂, was found to undergo an unusual transformation involving a double alkyl shift whereby the 鈭扖H₂SiMe₃ groups on the metal migrated to both pyrimidine rings. This migration afforded a final product that featured alkyl-functionalized, dearomatized ligand pyrimidine rings.