Terpenoids and Norlignans from Metasequoia glyptostroboides
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- 作者：Liao-Bin Dong ; Juan He ; Yuan-Yuan Wang ; Xing-De Wu ; Xu Deng ; Zheng-Hong Pan ; Gang Xu ; Li-Yan Peng ; Yu Zhao ; Yan Li ; Xun Gong ; Qin-Shi Zhao
- 刊名：Journal of Natural Products
- 出版年：2011
- 出版时间：February 25, 2011
- 年：2011
- 卷：74
- 期：2
- 页码：234-239
- 全文大小：783K
- 年卷期：v.74,no.2(February 25, 2011)
- ISSN：1520-6025
文摘
Four new terpenoids, metaseglyptorin A (1), metasequoic acid C (2), 12伪-hydroxy-8,15-isopimaradien-18-oic acid (3), and (鈭?-acora-2,4(14),8-trien-15-oic acid (4), and three new norlignans, metasequirins D鈭扚 (5鈭?b>7), were isolated from Metasequoia glyptostroboides, together with 15 known compounds. Structures of the new compounds were determined by analysis of their spectroscopic data, and the absolute configuration of 7 was established by the modified Mosher method. All of the compounds were evaluated for cytotoxicity against five human tumor cell lines.